by | Oct 8, 2024 | 0 comments

The Master Antioxidant: Glutathione, with Dr. Nayan Patel

Summary: 

Dr. Nayan Patel, a pharmacist and researcher, discusses the importance of glutathione, a tripeptide essential for human health. Glutathione acts as a powerful antioxidant, combating oxidative stress caused by free radicals. While the body naturally produces glutathione, its levels can decline due to age, stress, and other factors. Dr. Patel highlights the challenges of effectively delivering glutathione to the body, as previous methods like liposomal and intravenous delivery have proven ineffective. He discusses his research and development of a topical glutathione formulation that can effectively penetrate the skin and increase glutathione levels. Additionally, Dr. Patel emphasizes the importance of dietary glutathione, obtained from cysteine-rich foods, and the role of lifestyle factors in maintaining glutathione levels. Overall, the podcast provides valuable insights into the significance of glutathione for health and the challenges and potential solutions for optimizing its levels.

Full Episode:

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Transcription:

Megan Lyons: Thank you so much doctor Patel, for coming on wellness your way. I am very excited to have you here today.

Dr. Nayan Patel: It’s been a pleasure to come and speak to you today. Thank you for inviting.

Megan Lyons: Of course, I’ve read your extremely impressive bio to the audience, but why don’t you just start by telling us a little bit about you.

Dr. Nayan Patel: Well, if you talk about me personally, I talk about that, hey, I am, I’m a brother, I’m a husband, I’m a father, I’m a son. That’s what I am known for, for my work. I’m known as a pharmacist. And now recently, I’m doing more into research and development because of learning the chemistry has brought me to a very pivotal junction over the last 20 years. Is that, am I going to be peddling the drugs that the pharma company wants me to pedal or am I going to figure out something better way to do to help myself and my family first and then help the rest of the world with the better alternatives on helping healing your body from inside out. And so my journey has taken a pivotal point. And now we had a point where I can openly talk to people and letting them get into my world and see the work I have done and see if it can take on from here onwards.

Megan Lyons: That’s really incredible. And I’m grateful that you took what was probably the harder path. It’s probably easier to stay as a pharmacist, quote, in your lane and peddle the drugs and all of this kind of stuff. But you knew there was another answer. And I’m grateful that you are following that.

Dr. Nayan Patel: Yes, and most of my friends are still peddling medications because that’s, I mean, people need us. There’s no, there’s nowhere around people need.

Megan Lyons: Absolutely.

Dr. Nayan Patel: But then somebody has to get out of the pack and say, hey, you know what, there’s an other path someplace else. Let me go there. Let me figure out. I’ll come back and pick you up again. And so I’m here to pick people up now.

Megan Lyons: Fantastic. I love that you have recently really been diving into glutathione in particular, which will be a central focus of today’s interview. I’m interested to hear your take on how you got there, why you developed this interest for glutathione.

Dr. Nayan Patel: It’s been known for over 140 plus years that glutathione is probably the most essential element that exists on this planet that’s going to keep the humans alive and live forever. And I would say forever, but longevity, but nobody ever figured out how to actually enhance those levels inside your body. And so with all the medications we had in the world, they were not solving the problem. One day a physician came to me and asked me, said, hey, can you help me work on an antioxidant, vitamin C? And I told him that, hey, glutathione is a better antioxidant than vitamin C can be. I said, oh, no, no, no. Glutathione is too difficult. I’m not going to pay you for that one. Just help me make vitamin C. And so I said, you know what? I figured out that nobody’s going to do this work unless I do it myself. And so 1999, I basically started my journey on trying to figure out how to get glutathione as the molecule to help us for my patients health and wellness. And so it took me quite some time, but the molecule was just beaming in front of me. I said, hey, you got to work on this one. You got to work on this one.

Megan Lyons: That’s a calling right there. Very cool. And it’s been a journey that’s 25 years now. So it must be so important to have kept your attention. For those audience members that have never even heard the word before, can you start with the basics? What is glutathione?

Dr. Nayan Patel: So I’m sure people have heard about proteins, people heard about peptides, people have heard about amino acids. When the three amino acids comes together in a particular sequence, its a small tripeptide. That is what glutathione is, its combination of three different amino acids coming together in a particular sequence. And that peptide has an overarching job in your body to do multiple things. And so in the simplest term, its a very simple peptide, but in the overarching, its by far the most abundant peptide produced in the human bodies.

Megan Lyons: Amazing. Produced in the human body. That’s important for people to hear because we have so many people talking about various components that are exogenously produced or produced in a lab, and to hear, oh, wow. Glutathione is produced in the human body. I know that opens some people’s ears. So, uh, it’s a very important one. It’s captured your attention for this long. We refer to it as the master antioxidant. And I think people are relatively familiar with what an antioxidant is, but I’d love your take on that. Can you describe to the audience what an antioxidant does?

Dr. Nayan Patel: Oh, absolutely. So oxidation or oxidative stress or any simple rusting from your body inside. I always use the word rust because people can imagine right away. So, hey, they see a nail that is kind of getting rusted. That’s how the body gets from inside, is rusted because of oxygen. That oxygen species inside our body is important for survival. But overexposure to this species can also bring havoc in the body. And so the body produces glutathione to kind of quench the free radicals is what we call them. It’s just radicals that are out there with supercharged molecules. We got to somehow neutralize them. And basically, once they’re neutralized, they stop doing damage to the body from inside. So that’s what antioxidants are. They stop from oxygen molecules, nitrogen molecules, which are supercharged from running around and damaging the body from inside.

Megan Lyons: Yes. And what are the major contributors to oxidative stress or these reactive oxygen species?

Dr. Nayan Patel: Well, first of all, you breathe every second of your life, right? Oxygen is by far the biggest contributor. But then your body uses the oxygen and then it, it converts carbon dioxide and just. And you blow it out. But excess oxygen can also has an issue. So the oxygen stress comes out from, from multiple sources. The main source is environmental because we breathe in to air that are, some of them that are toxic. And so with the oxygen, you get other gases as well that you breathe in that can, that can. The body has to start processing them. Then the biggest issue we have is oxygen stress, or this species generated from your own bodys reaction. Because the body is a giant ball of chemical reactions happen every single second. How do you think that the hair is growing, the cells are growing, the eyes are growing. And if you get a cut, how is the body going to heal every single thing in your body? Because the body is constantly. Is this a chemical reaction? Happen every single second. The byproducts of this chemical reaction is also an oxygen species or nitrogen species that reactive, what we call them at excess of any of those things is called oxidative stress. And so endogenously, which is a body’s own reactions, and exogenously from breathing oxygen, air or other chemicals or other gaseous that we had breathe in, that can bring in this species inside our body.

Megan Lyons: Yes. And how do people know, based on labs? I don’t know if you have a favorite lab to measure this or even based on symptoms, if they’re having high oxidative stress, uncontrolled oxidative stress.

Dr. Nayan Patel: So, uh, it’s, it’s hard to measure oxidative stress down. So people do measure MDA levels is, uh, melan aldehyde levels, but typically nobody measures that.

Megan Lyons: Yeah.

Dr. Nayan Patel: Uh, so it’s like how much, when people say that, hey, how much oxygen is, is out there, nobody knows. But then they tell, they always measure, okay, from your fingers, they put over here, how much oxygen is your body able to breathe in? Right. So thats where we can measure that part. But oxygen stress is actually not being measured correctly. But what we do measure is what oxygen stress can do to your body. So if you have excess cholesterol, we can measure that part out. If you have any particular diseases that. That we know that caused by oxygen stress is, we can see those things out. And so the question is, do we want to measure oxidative stress down, or do you want to always keep this in check at all times since the day we are born? The answer is the second part, because everybody has it. It’s not like you don’t have it. Every single human being on this planet or any other planet, for that matters, right? They have oxidative stress. Everyone has it. The question is how. How much is it?

Megan Lyons: Yeah.

Dr. Nayan Patel: Right. Is it, is it, is it gone overboard that’s causing diseases now? Or is it, is it, is it under check?

Megan Lyons: Yeah, and under check. So if every single one of us is breathing, hopefully every moment, and doing other lifestyle things, even over exercising or. Or whatever else that can contribute, eating inflammatory foods can contribute to oxidative stress. Is our glutathione production adequate to control that oxidative stress, or do we need some glutathione support from food or supplements to help with that? So if we go down this path, how do we get glutathione outside of supplements? For now, just start with foods. How do we get glutathione to control this oxidative stress?

Dr. Nayan Patel: Absolutely. So first question you asked me is that, hey, do we have ways to improve glutathione levels? Does our body produces enough glutathione level? The answer is yes. On average, I would say, I don’t know 90 plus percent people in the world until the age of 30, the body is able to keep up with all the demands. You have all of them, right. It can produce enough glutathione to keep the oxygen stress unchecked at all times. Now, I said 90% plus. There’s small percentage of population that we know they have a gene defect or gene mutation or something where the body is able to not produce enough glutathione or. Or the oxid stress is high to begin with on the way they process all the chemicals exposed to our daily basis.

Megan Lyons: Yeah.

Dr. Nayan Patel: So there’s gene mutations nowadays. I mean, for the last 15 plus years, everybody’s able to test it at a very reasonable cost. 15 years ago, this was cost prohibitive for us to test for genes, to see what gene mutations do we have today? It’s affordable. A lot of people are doing it all the time. And from that data, we are finding out there’s a certain population patients are not able to produce enough glutathione or, you know, keep up with the demand. And so for those people, they need to supplement them with food or just taking some vitamin supplementations to begin with. So the second part of the question you asked me is that how do we improve the glutathione levels? Two ways. One, which is easy to do, is to reduce your exposure to known chemicals or toxins, including alcohol, which you use up a lot of glutathione. Uh, reducing exposure so that your body can keep up with the demand.

Megan Lyons: Yeah.

Dr. Nayan Patel: And the second part is, what does the body needs? Three amino acids, right? Glycine, glutamine and cysteine. By the way, your body has enough glutamine coming into, into you from, from various foods that you eat on daily basis. So I would not supplement glutamine at all. If you have to supplement, I would look for cysteine rich foods. And thats what should be your name, that should be your diet. Right. Anything that has high amount of cysteine should be like a staple diet that you have to eat every single day. Right. And so, I mean, people are vegetarian, theyre vegan, theyre carnivore, and every food sources has enough cysteine in there. So just have to put in a famous search engines, put out cystine rich foods and get a list of foods that you can eat and pick it out. What, what do you like? And I think they also mention how much cysteine you get out of each food. I mean, I love whey proteins. I love Brazil nuts. Uh, of course, you get from turkey and chicken and, uh, avocados and asparagus. And if you can get it from the food, it’s much, much, much better than getting from a supplement. The subway, you only get one thing, the foods. You get a complex, you get other, other proteins, other amino acids along with it. Uh, so it’s always better to get from your food than the vitamin.

Megan Lyons: Interesting. Great. And I love that you mentioned so many diverse types of foods. That’s amazing. You did mention alcohol in there, which I see as a form of stress to your body. So you can take this just as alcohol or broaden to other types of stress. I’m curious your thoughts on how stress impacts glutathione levels.

Dr. Nayan Patel: We haven’t got into that part yet, but I’ll start dive into that part because the second portion of glutathione that nobody talks about is the detoxification, activation of all the detoxification pathways inside your body. And that is by far much more effective and needed to a body than the antioxidant benefits that you see. Right.

Megan Lyons: Wow.

Dr. Nayan Patel: And so how do we keep our body clean from inside? So that part, the detoxification pathways are multiple effects on your liver by conjugating those things. So if we can reduce the chemical load inside your body, the stress also reduces. When we measure stress, we only measure stress on your adrenal glands, which is. Right. It sits right above your kidneys. That produces cortisols and adrenaline and all those. All those good hormones that you. That you are always excited about to do some things. But that in the moderation is great, but in the modern day society, we overproduce these hormones today. I mean, young kids are what we call them as adrenaline junkies. Right? They get bored. Extremely easy.

Megan Lyons: Yes.

Dr. Nayan Patel: If they not engage every single second of your life within two minutes. Dad, I’m bored. Mom, I’m bored. What am I supposed to do now? I said sit down, relax, calm yourself down. Do meditations if you have to do yoga, do something, exercise, just calm yourself down, give the brain some time to breathe. And we don’t do that part. When you say stress, it’s a big old thing. So I want to make sure I address that stress issue as a point of detoxification, because if your body cannot detoxify, the stress never leaves you.

Megan Lyons: Yeah.

Dr. Nayan Patel: The stress starts building up over time. And so when we talk about stress, the oxidative stress that we discussed earlier, there’s chemical stress that we talk about alcohol and exposure to other chemicals that we either we’re putting the form of a makeup of the foods we eat or exposing yourself to some chemicals. And the third thing is the psychological stress. So keep in mind, I’m going on and on. Sorry.

Megan Lyons: No, it’s fantastic. Keep going.

Dr. Nayan Patel: That your brain consumes 20% of all the oxygen you breathe in. Your brain is only 2%, 2% of a total body weight, but yet it consumes 20% of all oxygen you breathe in. The highest amount of stress you have in your body, toxin. Stress in your body is in your brain.

Megan Lyons: Wow. I didn’t know that.

Dr. Nayan Patel: So if you are at the age of saying that, hey, you know what? I’m forgetting little things here and there. There’s a sign the stress is getting higher right now. If you go fast forward, you don’t fix this problem, and you go fast forward, you started getting into dementia or early onset Parkinson’s or ALS or Huntington’s disease. And, I mean, you can name the disease out there. Guess what? There’s zero cure or solution for all these diseases today.

Megan Lyons: Yes.

Dr. Nayan Patel: So science, in the last God knows how many thousands of years have not caught up to any solution for brain disease.

Megan Lyons: Yeah.

Dr. Nayan Patel: And yet we are not doing everything possible to resurrect stress down.

Megan Lyons: Yeah.

Dr. Nayan Patel: And in this day and age right now, the advent of all this modern technology, that we will not get rid of it anymore, our mental stress has is an all time high right now. So if you do not sit, I mean, the simple thing is that would you sit down and eat your lunch, or would you just eat your lunch while walking?

Megan Lyons: I would sit down and eat my lunch. I will admit that I have eaten my lunch while walking before, but I certainly would not recommend it.

Dr. Nayan Patel: No, of course not. And the thing is, we got to start slowing things down. And so that’s what I think the simple joy of eating food is gone now. Food is a meat of just a fuel, and just stuff it in there and let’s keep on going. I said no.

Megan Lyons: Yes.

Dr. Nayan Patel: Embrace your body. Do the right things. De stress your life down. Enjoy the life. Smell the roses if you have to. Right. Every day. So, these are the kind of things. So when you talk about stress, I want to address that part first. And now you can ask me any question about stress now.

Megan Lyons: Well, I think this is really interesting. And tying it back to what you said before, it’s this complex interplay between, potentially, our genetics. I don’t know if you’re using actual glutathione producing genetics, maybe GTSM, or if you’re using something like sod two genetics or whatever, but I don’t think we even know exactly every single gene that plays into this. Maybe you do, I don’t. But there’s this genetic interplay combined with this influx of stress. There’s physical stress, there’s emotional stress, chemical stress, all of these stressors. And it seems like we’re just in this cesspool of, oh, my goodness, our bodies need so much glutathione, and our body can’t keep up with it. Is that what you’re saying?

Dr. Nayan Patel: It is. It is what I’m saying. And the thing is what we have figured out, that in the modern society that we have right now, that up until the age of 30 ish, right? It depends on how healthy your diet and your lifestyle is. Up to the age of 30, your body’s need of glutathione and how much you can produce is about the right amount. Starting the age of 30, your needs doesn’t change. But your ability to produce glutathione starts changing slowly.

Megan Lyons: Yes.

Dr. Nayan Patel: And the slight change affects who first?

Megan Lyons: Stress people?

Dr. Nayan Patel: No. Your creepy forgetfulness starts kicking in. At what age does you start forgetting things? And we call it, oh, it’s the mom’s blues. Because most moms get pregnant by the age of 30. 35 ish. Right. 35 is kind of late, but that’s okay. Oh, I got a mom brain now. Right.

Megan Lyons: Interesting. Yeah.

Dr. Nayan Patel: But it’s reality is that now the oxal stress is slowly, slowly increasing. Not enough to do any damage at this point.

Megan Lyons: Right.

Dr. Nayan Patel: Nothing is broken yet. But guess what? It’s changing. It’s slowly, slowly changing to a point where your body is now feeling the effect of having excess stress.

Megan Lyons: Yes.

Dr. Nayan Patel: And so no diseases onset yet. Maybe five or ten years down the road, you can start seeing creepy, creepy creeping up, all these diseases kicking inside your body. But if we can somehow improve the diet and go back on track again, guess what? We can recreate this balance for another day in time, which is up until 40. After 40, it becomes extremely difficult to keep up with the demand. It’s very, very hard to keep up with the demand.

Megan Lyons: Got it. So you’re mentioning brain fog and mom brain, and this is happening between 30 and 40. What are some other common symptoms if someone can’t keep up with their glutathione.

Dr. Nayan Patel: Needs fatigue, inability to detoxify your body. So that way you have aches and pains in the body. Your sleep patterns are kind of not very good. Uh, generally you become sluggish overall. Right. And you always, every time people get sluggish. Oh, you’re just getting old. I said, no. God no. Have you seen an 82 year old man competing in Ironman?

Megan Lyons: I love this stuff. I was just watching a 90 year old woman competing in the the decathlon, which I think is fantastic. So there are people out there, but certainly most of them are not.

Dr. Nayan Patel: Well, I had one of my doctors that. That I worked with, and at the age of 81, he completed Iron man.

Megan Lyons: Wow.

Dr. Nayan Patel: He met his daughter, both the daughter in what? I think the daughter was in late fifties, I believe so. Or early sixties. And he was 80 plus. And they both completed the same race. And he was first in his age group.

Megan Lyons: Well, maybe he was the only one.

Dr. Nayan Patel: But still, that’s why he was the only one. That’s why.

Megan Lyons: That’s great. I hope I’m the one who is the only one in their age group sometime. That’s really fantastic. And on the same token, I have seen my grandparents and parents to some extent. I have three grandparents who I lost in their sixties and seventies, and my one grandfather’s about to turn 100 next month. And his energy, though, for the past, I don’t know how many decades, has been really slow. So I think it’s very familiar that people are seeing these symptoms and they see the other side, that it doesn’t always have to be that way.

Dr. Nayan Patel: It does not. And I’ll give a simple example. So my dad, at the age of 70, I would say 79 or no, 77. At the age of 77, he had a, uh, he had a blockage in his arteries, so doctor would have put a stent in there, open up the artery so he can breathe, so he can, the blood flows better. So he was fine. Right. At about the same time is I made the discovery of this glutathione. I have not launched the public yet. Right. So he was patient number one.

Megan Lyons: Wow.

Dr. Nayan Patel: He was, he used it for ten years until he was 89.

Megan Lyons: Wow.

Dr. Nayan Patel: Guess what I mean. He had arthritis, he had type two diabetes, and he was slow and lethargic and fatigue out. When people have diabetes and arthritis and blood pressure issues, you dont function normally, youre always slow. In the last ten years, he walked on average from three to 6 miles every single day.

Megan Lyons: Wow.

Dr. Nayan Patel: Traveled the world. He traveled the world by himself. My mom passed away 20 plus years ago. So hes single, he lived with us. He traveled the world. Only thing we had to do for him is just buy him a ticket, and off he went. He just went on his own.

Megan Lyons: That’s incredible.

Dr. Nayan Patel: Carry the bag and just go away. Boom. Was gone. And he had so much energy. And all his friends will come to my house and tell me, what in the heck are you giving? What kind of pills are you giving to your dad? I want some of those things.

Megan Lyons: Yes.

Dr. Nayan Patel: And my dad told me not to tell anybody because they will try to criticize you and theyll tell you, say, hey, kind of slow down, because if you cant keep up with them. But the idea was that your body can heal at any age.

Megan Lyons: Yes.

Dr. Nayan Patel: Age is just a number. If I can get an 85 and 89 year old man walking 6 miles a day after being type two diabetic arthritis and blood pressure for decades, anybody can, can heal themselves.

Megan Lyons: That is right. That’s an amazing story. And now I see even more why you’ve been so personally invested in this. So I want to start talking about your current formulation of glutathione. But let’s start by talking about different methods of delivery. So if people are listening they’re saying, yes, I have the mom brain. Oh, my goodness. I don’t want, I’m starting to have fatigue. I do have a lot of stress, chemical, emotional, physical, whatever. I want to get some more glutathione. The format has been pretty widely debated. I remember, I don’t know, maybe a decade ago when liposomal got very popular and people are like, okay, now we figured it out. We’ve got liposomal glutathione, but maybe it’s not actually increasing the levels in our body. And then some people say, use precursors to glutathione and don’t even try with glutathione. So talk to us a little bit about the formats and then why you’ve wound up where you are now.

Dr. Nayan Patel: Absolutely. So let me start off with first things first. All the precursors comes from your diet.

Megan Lyons: Interesting.

Dr. Nayan Patel: So please, please, please don’t stop eating. Yes, eat, eat right foods. And if you have to eat the right foods, figure out which foods gives you the best nutrient values and consume those foods. Right again, cysteine rich foods. Type it in there, get a listen and make sure that you have those foods every single day. That’s number one.

Megan Lyons: And I’ll put a list in the show notes. I’ll find a good list of cysteine Richards and put those in the show.

Dr. Nayan Patel: Thank you for doing that. The second part is that back in the sixties, FDA approved precursor, which is n acetylcysteine. Cysteine itself, it’s very pungent, smells very sulfury, and is very hard to stabilize them. So an acetyl form of cysteine was approved by FDA as a supplement, as a drug to enhance glutathione levels. So even today, even this is, we’re talking back today, 40, 50 years later. Right. Even today’s date, if you end up in a hospital with tylenol overdose, right, the first thing they give you is the NSLO cysteine. That’s FDA approved molecule to detoxify the thyroid out of your system, acetaminophen out of the system. And basically you are up and functioning in. Right. That’s still even today’s, that’s, that’s a drug of choice that never went away. So back in the sixties till today, how come FDA has never approved any of the medications besides that one precursor? Thats the question you asked me. So how do I get glutathione in my body? Thats the reason why no other medical has been approved because nothing actually worked correctly. Right. So back in the nineties early nineties, there was a research trial done. They infused the glutathione into the veins. And what they found out was when you infuse the glutathione straight up, it increased the cysteine in your body, but not the glutathione.

Megan Lyons: Interesting. Okay.

Dr. Nayan Patel: And so the body was breaking down the glutathione and getting rid of it. Yeah, but then it absorbed the cysteine, and 90 minutes later, they saw a rising glue thyroid level.

Megan Lyons: Very cool how the body’s so smart.

Dr. Nayan Patel: Yeah. So the glutathione levels did rise. No doubt about it. The levels went up, but not because the body absorbed the glue thigh.

Megan Lyons: Right.

Dr. Nayan Patel: The body broke down the glutathione into amino acids, absorbed the cysteine as an amino acids, and used it to produce glutathione.

Megan Lyons: Interesting.

Dr. Nayan Patel: That was in the early nineties.

Megan Lyons: Okay.

Dr. Nayan Patel: Then in late nineties, when the doctor came to me to make the vitamin C, I took upon myself. And in 1999, we made the first liposomal glutathione product.

Megan Lyons: 1995, wow.

Dr. Nayan Patel: 1999.

Megan Lyons: Oh, 99 still, that’s a long time ago. I just said ten years ago, but clearly I was way off.

Dr. Nayan Patel: So I made the glutathione, I made vitamin C, I made some coq ten product at that time. And what I found out two and a half years later is that the liposome form of glutathione, even though it may be working for some other molecules, for glutathione, it was not giving me predictable results. Maybe my technique was wrong of making liposomes. I dont think so, but I could be wrong on that part, too. Anyway, regardless, it did not work for me and my patients.

Megan Lyons: Okay.

Dr. Nayan Patel: So quickly I started working on newer technology. I said, hey, I got to work on something else. And at that time, polysaccharide, dextron molecules were, were there, but there was nothing being done in the whole world. Nobody’s ever made a medication out of it. Nothing was done. It’s all in R and D phase. Nothing was going on. And so we use that molecule to somehow figure out, can we use that to stabilize glutathione? And in 2007, we were able to, for the very first time, stabilize the glutathione in my lab.

Megan Lyons: Wow. Amazing.

Dr. Nayan Patel: Stable molecule. Got everything done. And then it smelled pungent. Right? Smell has a sulfur smell when we apply on the arm, it was sticky. When we put it in the mouth, it was taste awful. We sprayed the nose. It burned my nose. I said, uh oh. I said, it’s not going to go through the nostril taste awful. I cannot master taste. So the only option I had left was the skin drought.

Megan Lyons: Yeah.

Dr. Nayan Patel: And glutathione is a large molecule cannot go through your skin. I said, okay, now what? Right? So we use another technology to kind of twist the molecule because there was protein, animal being method was out in the literature, but nobody’s ever made a drug out of it or product out of it. So I say, you know what, let me, let me work on it. It’s a very small, it’s a trip, it’s not a protein, it’s a tripeptide. It’s a three amino acids. It’s a simple molecule. I can twist it. So that’s what we did. And by 2009, we had the first stable molecule getting through your skin available to the public. Well, we didnt make it public yet, but it was available for the very first time. And he goes, okay, now what? So then I quickly found out that the dose that talked about in the literature was too high. When we applied that much dose topically, people were having some reactions. Uh oh. So there should be no reactions. There should be zero reactions. What we found out was this particular product was actually getting in such a bloodstream within seconds, if not minutes. Right. So it was going too fast. And when it gets too fast, your body starts working right away. It’s like, for example, if I give you a million bucks right now, cash in your hands, and say, hey, go start shopping, guess what you’re going to do? You could spend it right away.

Megan Lyons: Yeah, right away.

Dr. Nayan Patel: Instead, if I give you a million dollars worth of bonds. Okay, you know what? I got to try to figure out, cash it out, put in the things, do other work, get my advisor to help me get this thing done. By the time I get the money in my head, 30 days out, and then I’ll use it up. I’ll still be able to use it up. But see, with this, giving glutathione straight to your body, immediately, the body started processing really, really fast. Was too fast. And so then I figured out, I said, okay, this is not going to work. I had a bunch of doctors working with me. I said, hey, Dan, we can do this easily. Let’s just figure out what dose to give them. And once I know the dose to give them, we can do it. So anyways, long story short, we did the dosings, we did some patient trials, and we give the medications to the patients. We work with physicians, they wrote prescriptions for every single thing. And for 13 years, we worked on it together to figure all these things out and then eventually launched the product in 2020. By that time, for 13 years, I was writing the book the glow down revolution. I’ve wrote the book, put up my findings inside, and I released the book before I even launched the company.

Megan Lyons: Oh, bummer. Well, maybe good. Hopefully it brought you attention, because it.

Dr. Nayan Patel: Didn’T bother me, because my thing was to get the information out of the public as fast as possible. But the launch of the product was going to depend on when I was ready. Yeah, not when the people were ready. People were ready 100 years ago. Right. They didn’t have product, but I was not ready to launch to the public yet. So once I get my data in completely, everything was great. There was no problem whatsoever. Patients were getting great results and outcomes. I said, you know what? I’m time to launch the products. So that’s the history, that’s the story for my topical products. So intravenous did not work. The liposome technology did not work. I mean, they all work to a certain point because the body breaks down the amino acids, absorbs amino acids, so the levels will rise. So don’t get me wrong. If you do iv’s, if you do liposomes, if you do oral capsules, they all work the body, break it down, absorb the amino acids, use the aminos to produce the glutathione, and there you go. But here’s the kicker. You will never be able to produce any more, any more than a certain amount. And that’s another amount is determined by the, by your own body’s ability to produce that, that, that glutathione. With the topical version, I can go as high as I can give you.

Megan Lyons: Got it.

Dr. Nayan Patel: So sometimes if your needs are very high, I can give you as much system as possible, but your body cannot produce so much. If your needs are over here, your body only going to produce up to here.

Megan Lyons: Yeah.

Dr. Nayan Patel: All the technology, product that’s out of the market and you can get up to here, maybe, right. But you never get to the point. And so with the topic conversion now, we are able to replace the glutton levels up until the high normal.

Megan Lyons: That’s a really important point. So I want to reiterate, to clarify and make sure that I’m getting this right and make sure the audience understands. So when you’re taking liposomal, oral iv, any kind of glutathione that’s not topical, it does work to increase glutathione levels, but it relies on your body to do the breaking down. Process and reassembly process. And there’s a cap. You can only do so much. Each person can only do so much. But if your needs are super high, even if you’re taking all the iv glutathione and your body just can’t put reassemble those three peptide or three amino acids together, you’re not going to get as much as you need versus topical. That whole molecule, because it’s twisted, is somehow able to be absorbed so you can dose at higher levels and you don’t rely on the body putting it together. Is that right?

Dr. Nayan Patel: 110%. Thank you for doing that. Okay. I was going on and on about different ways, so you put it such a nice and easy.

Megan Lyons: Well, you helped me understand it. I really appreciate. I actually didn’t know that that was the way it works. The audience, if they’re listening closely, will probably think, oh, well, that’s similar to how we’ve talked about collagen before, which collagen, again, is a sequence of amino acids that your body breaks down and then can put back together again. So this is really cool that you figured out the way to get it topically absorbed. Now, you did mention before that the topical version smells. So just prepare the audience a little bit. What does it smell like?

Dr. Nayan Patel: It smells like sulfur.

Megan Lyons: Okay.

Dr. Nayan Patel: The smells does dissipate pretty fast, because when you apply and you, when you rub it in, it literally, like 50 to 50, 90 seconds, it’s already gone. It’s already gone inside your body. So the smell’s gone. So you cannot smell anymore. Uh, smell. God. The polysaccharide molecules that we use to twist the whole molecule of glutathione is a little sticky, a little tacky, but if you rub it in, that should go away as well. So tackiness goes away, the smell goes away. It should be pretty, pretty smooth after that.

Megan Lyons: Uh, great.

Dr. Nayan Patel: So, yeah, it is. It is part of the thing. And I’ll tell you, the formula I had in 2007 and the formula I have today is identical.

Megan Lyons: Interesting.

Dr. Nayan Patel: I was, I could not. For the last 15 years, I have not able to change the texture, the smell, or any other components inside the whole complex. It’s, it’s like I, it’s. I’m a spiritual guy. So something tells me is that, hey, this was, this was a gift given to me.

Megan Lyons: Yes.

Dr. Nayan Patel: Somebody higher power.

Megan Lyons: Yes.

Dr. Nayan Patel: And it’s such a simple molecule that I can change anything from it.

Megan Lyons: Yeah. Really interesting. You’ve tried other ways, and this keeps coming back to you, so it must be meant to be.

Dr. Nayan Patel: I’ve done over a hundred different iterations of this molecule. Different ways to figure out the smell, the texture, uh, anything. Uh, if I can add some, uh, some other fragrance inside. Not a fragrance, but essential oils and things like that with water base. Nope, doesn’t work. It does not work. Anything that goes inside just breaks it apart. Boom.

Megan Lyons: Well, personally, I’m willing to do a lot of things for my health, and to have something a little smelly and a little sticky for a few minutes does not faze me at all. And I think most of our listeners will be on board. I just wanted them to be prepared. But I’d love to hear, since you’re the super expert in this and you seem like a healthy guy, how do you use it? Do you increase dosage at certain times? Do you use it every day the same amount? What do you recommend?

Dr. Nayan Patel: So, okay, so the baseline studies that we have done, we have done like, we’ve done some blood testing, we done some human trials as well. We did at the university local in California, did a human trial for 30 patients. Trying to figure out, does it stay in the body? For how long does it stay, what dose to give you things like the absorption is there or nothing? And what we found out is about. It’s about four sprays of glutathione, which is the. Glittery is the name of the product. I’m sorry.

Megan Lyons: No, it’s okay. You’re welcome to say it. Please market it.

Dr. Nayan Patel: Glitteril is the name of the product. Four sprays of that one, which gives you about 0.5 ML, gives you approximately 100 milligrams. And if you do that twice a day for, I would say 90% plus people, that is absolutely more than sufficient.

Megan Lyons: Okay.

Dr. Nayan Patel: Right. It’s more than sufficient. My schedule is very erratic. I’m traveling all the time. I’m in different time zones all the time. Before zoom. Thank God for the zoom. We can do now this remotely, but even then, people want to see me face to face and discuss, and I do a lot of speaking engagements. So when I’m traveling, I end up using eight sprays, twelve sprays twice a day. I have gone as much as 16 sprays twice a day. Some of the hotel rooms have carpet thats moldy in there, and so its very difficult. And I already have personally have mold issue from traveling from all these things. So I keep everything in check. As long as I have my glutathione, everything is in check for me. So when Im home, four sprays twice a day is all I need. And I’m traveling, I may have to use a little bit higher. I’m also guilty of drinking an adult beverage once in a while, usually once every other week or so, I’ll have a beverage or two. If I do that for that day, I will double or triple the dose. I’ll probably before and after my drinking as well, because I want to metabolize all this alcohol as fast as possible. It’s not going to affect the buzz or anything else like that, but it’s going to process the alcohol out of your liver pretty fast. So that way, you know, it’s your body start to get rid of it as fast as possible. So I always do more.

Megan Lyons: That’s really amazing. So connecting back to what you said at the beginning to help the audience recognize whenever you’re under more stress, whether that’s stress from time zones, emotional stress, or physical mental stress from doing all these presentations, chemical stress from whatever they’re using to freshen up the smell in the hotel and the mold in the carpet or alcohol, any of these stressors that increase, you’re just matching. You’re supporting your body by giving it a little bit more glutathione so it can continue doing its job. And maybe the perceived stress on your body goes down because of that.

Dr. Nayan Patel: Exactly. And there’s another stress, which is sunlight. Right. Sun exposure, but a lot of stress. But keep in mind, your body will recycle the glutathione. Half of the body’s glutton gets recycled. So if youre in the sun all the time and getting sun exposure or youre breathing oxygen normally every day and not doing anything crazy, uh, like crazy means, uh, exercising like 2 hours a day and heavy breathing, things like that. Now youre consuming. Youre opening up the lungs and consume a lot more oxygen. That is a lot of stress produced that has to be quenched. But normal breathing, normal exposure, sunlight, you dont have to increase the dose for glutathione. The body will use up and recycle, use up and recycle. Use up and recycle again, over and over and over again. So you dont have to take extra for that one. But yes, extra stress, chemical exposure, alcohol exposures and things like that, mold exposures, things like that. Your body will use up the glue without reserves, and so you have to replenish them again.

Megan Lyons: This is amazing. Well, something as simple, simple sounding as glutathione has turned into such an interesting conversation. I know the audience wishes it was three more hours, but in the interest of time, I have two more questions for you. One is, I would actually love you to tout your specific product. Tell us where to get it, the brand name again, all of this, and we’ll link in the show notes. And then two unrelated to that. If there’s one health habit that you do personally that’s not related to glutathione, I’d love to hear that.

Dr. Nayan Patel: So the best health habit that I’ll go with habit first. I’m sorry.

Megan Lyons: Sure. Great.

Dr. Nayan Patel: The habit that. That has really helped me, and it has worked for me because my mind, I cannot shut down my mind. My mind is always, like, going 100 miles an hour at all the times. Meditation, morning and evening, deep breathing, focusing on one thing. When I say meditation, there’s multiple ways of doing that part, but just calming myself down. Right. Staying homeostasis right in the middle. Not super excited, not depressed, but right in the middle. Right. And that has been a focus. And I can only do maybe five or ten minutes a day, twice a day. That’s all I can do.

Megan Lyons: That’s great.

Dr. Nayan Patel: But I try to do that every single day. Like, even like right now, right before this meeting we had today, I sat down for about two minutes, did box breathing, so that I can calm my nerves down and be focused on the message I’m trying to deliver to all your audience.

Megan Lyons: Amazing.

Dr. Nayan Patel: Because if not, I’ll be all over the place. I’ll go on a tangent all the time, but I need to stay focused. So that’s the work.

Megan Lyons: You’re a great testament for meditation because you really delivered a ton of information today. So now please talk about your product.

Dr. Nayan Patel: So the product is available on my website. It’s aurora.com. a as in apple u r o wellness. Wellness.com. there’s only two products I have, which is a gluteral and glittery plus. The plus is a stronger version of glutathione. And this is mainly for people. Uh, they have very high needs of glutathione. Uh, there are a lot of diseases that are linked to oxidative stress. And if you have, uh, if you have one of those diseases that link to oxidative stress, then you might need a higher dose of glutathione initially to replenish all the reserves. But once you get balanced and you can switch over to the regular gluteal and maintain that level for rest of your life, initially, you may need to go higher dosages. So that’s why we made the plus version. Most of the plus versions that are used, most of the people that recommend this product to us are physicians themselves. So a lot of physicians, they stock them in their own offices, and they will have it available for you too, as well. So if you work with a doctor, the stocks are there. They’re more than likely getting from me. So you’re okay to take it buy from them directly as well. If not, my website will be the next best choice.

Megan Lyons: That’s fantastic. We will link to that below. And I want to thank you one more time for this wealth of information that you’ve provided. I really appreciate you sharing some of that with us and sharing some of your time.

Dr. Nayan Patel: Well, thank you very much. I appreciate it.

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Want to hear about this topic in audio format? → Check out the podcast episode here!

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Hi! I'm Megan Lyons,

the voice behind The Lyons’ Share. I love all things health, wellness, and fitness-related, and I hope to share some of my passion with you. Thanks for stopping by!
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